Highly Mimetic Ex Vivo Lung‐Cancer Spheroid‐Based Physiological Model for Clinical Precision Therapeutics (Adv. Sci. 16/2023)

نویسندگان

چکیده

Biofabricate Lung Tumors In article number 2206603 by Mien-Chie Hung, Der-Yang Cho, Yi-Wen Chen, and co-workers, a facile route to construct sophisticated ex vivo lung tumors models consisting of patientderived tumor spheroids, vasculature barrier, bovine ECMs, which maintained radial oxygen gradient, as well biophysical biochemical behaviors the native is established. This model demonstrates excellent prediction results (accuracy: 85%; sensitivity: 86.7% specificity: 80%) for applying in patient-specific precision therapies.

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ژورنال

عنوان ژورنال: Advanced Science

سال: 2023

ISSN: ['2198-3844']

DOI: https://doi.org/10.1002/advs.202370101